GPL SNP1000 is the most comprehensive test for alterations in the genetic code in the pathways that are most important for integrative medicine. This test looks at nine core groups of genes which are crucial for many different biological pathways. Previous to GPL-SNP1000, most genetic tests have only looked at a small subset of genes and very few SNPs (single-nucleotide polymorphisms). GPL-SNP1000 includes over 1,000 different SNPs and over 144 different genes. Here are the pathways that GPL-SNP1000 assesses:
•Mental Disorders / SAM-E/B12 Metabolism
•Gluten Opioid Peptide Homeostasis
•Autism Spectrum Genes
Protected: Fitness & Diet Genetic Test
Due to our genetic makeup, we are all different in many ways. There are the physicial differences such as eye and hair color, but then there are the differences inside us such as how we metabolize nutrients, the way we deal with toxins etc. We all interact with the
environment in our own unique way. The fitness & diet genetic test helps identify an individual’s genetic predisposition for sporting or fitness profile, idea diet, and personal nutrition needs based entirely on genes.
Whole Genome Sequencing
Human whole genome has approximately 3 billion base pairs of nucleotides. The first human whole genome sequencing (hWGS) was completed and published in 2001. Since then, hWGS is widely studied in the filed of biomedical science, anthropology, forensics and many more. Individual variations, such as single nucleotide polymorphism (SNP), copy number variation (CNV) and structural variations (SV), can be identified by whole genome re-sequencing.
Retinal Degeneration Panel
Mutations in more than 60 genes are known to cause nonsyndromic retinitis pigmentosa. Mutations in any of the genes responsible for retinitis pigmentosa lead to a gradual loss of rods and cones in the retina. The progressive degeneration of these cells causes the characteristic pattern of vision loss that occurs in people with retinitis pigmentosa. Rods typically break down before cones, which is why night vision impairment is usually the first sign of the disorder. Daytime vision is disrupted later, as both rods and cones are lost. Retinitis pigmentosa often has an autosomal dominant, or autosomal recessive , or X-linked pattern.
Metals Hair Test
Heavy metals toxicity caused by increasing levels of pollution and use of chemicals in industry is a growing threat to our health and development of our children. High levels of toxic metals deposited in body tissues and subsequently in the brain, may cause significant developmental and neurological damage. A Metals Hair Test is ideal for checking current exposure to toxic metals. Hair provides important information that can assist the practitioner with an early diagnosis of physiological disorders associated with aberrations in essential and toxic element metabolism.
GynPlus is a next generation sequencing panel that simultaneously analyzes 9 high-risk ovarian and uterine cancer susceptibility genes Genes on this panel include BRCA1, BRCA2, EPCAM, MLH1, MSH2, MSH6, PMS2, PTEN, and TP53. These nine genes are associated with four hereditary cancer syndromes hereditary breast and ovarian cancer (HBOC), Lynch syndrome, Cowden syndrome, and Li-Fraumeni syndrome, all of which have published management guidelines. Identification of a mutation in one of these genes can help estimate cancer risk and guide treatment, screening, and/or prevention decisions for the patient.
Urine Hormones Metabolites
Test assesses both parent hormones and their corresponding metabolites, it reveals how the body is breaking down key hormones like estrogens, progestogens, androgens, cortisol and melatonin. This testing gives insight into whether we are fully detoxifying our hormones, which is important because some hormones can be carcinogenic if they don’t break down properly – leaving us more at
risk for a variety of diseases, like cancer.
Testing neurotransmitters in patients with psychological conditions can help target specific imbalances – getting to the root of persistent issues such as adrenal dysfunction, mood disorders, lack of ambition and lack of appetite. Neurotransmitter testing gives practitioners a diagnostic edge over the traditional psychological inventory. It offers the advantage of zeroing in on which therapies are best suited for an individual patient. Combining neurotransmitter testing with other hormone testing gives practitioners an even deeper insight into a patient’s Individual neurochemistry.
Cardio Metabolic Profile
Risk for Cardio Vascular Disease and Diabetes II is known to be particularly high in people who have a disorder known as “metabolic syndrome”, which is often associated with being overweight. CardioMetabolic Profile tests blood markers that can identify people at high risk of these diseases. If levels of several of these blood markers are abnormal, this should be an important “wake-up call” to tackle the problem. Biomarkers such as In, hsCRP, HbA1c, TG, CH, HDL, LDL, VLDL) are used to asses risk factors for the metabolic syndromes.
Food Allergy Panel
Food allergy occurs when the body’s immune system reacts to a protein in a certain food, causing the release of antibodies and histamine. The release of histamine causes symptoms. Allergy symptoms can begin within minutes to 2 hours of eating the problem food. Symptoms can vary from mild to severe. Even tiny amounts of a problem food can cause serious reactions in very sensitive people. Occasionally, a very severe, rapidly progressing and life-threatening allergic reaction, known as anaphylaxis, can occur. This requires immediate first aid treatment, for example with an EpiPen adrenaline injection. True food allergy is most common in children, but only affects about 1% of adults. Most children will grow out of food allergies by school age, although seafood and nut allergies tend to be life-long.
InSure® FIT™ is a CLIA waived test that is available for Physician Office Lab (POL) testing. To help improve
colorectal cancer screening compliance, InSure®FIT™ screening test offers high sensitivity and ease of use. It is a highly patient-friendly water-Based collection method. It’s patented brush sampling replaces unpleasant fecal collection or smearing and there are no dietary or medication restrictions. InSure® FIT™ has 87% sensitivity for colorectal cancer & 98% specificity. The test has a 66% increase in patient compliance versus a guaiac-based fecal occult blood test (gFOBT) based on a recent study1.
New Born Screening (NBS)
Newborn screening identifies babies with treatable congenital disorders to prevent adverse outcomes. All of the disorders on the newborn screening panel can be detected by a blood spot collected on filter paper after 24 hours but within 48 hours of birth.