Karyotyping – Chromosome Analysis
Karyotyping for Recurrent Abortion (husband and wife):
Spontaneous abortion occurs in 12 to 15 percent of all pregnancies. A subset of patients habitually abort in the first or second trimester. Studies have shown that the risk of recurrent spontaneous abortion is much higher in this subset. Family physicians are likely to encounter the problem of recurrent spontaneous abortion and must address both the medical and psychosocial implications. This article reviews the literature and offers an approach to the management of patients with recurrent spontaneous abortion.
The most common cause of sporadic spontaneous abortion is a chromosomal abnormality of the fetus. More than 60 percent of first-trimester fetal losses show some type of cytogenetic abnormality. The most common abnormality is aneuploidy (an abnormal chromosomal composition), with autosomal trisomy accounting for more than 50 percent of chromosomally abnormal abortuses. Other common types of aneuploidy include XO, XXX, XXY and XYY. Polyploidy accounts for approximately 22 percent of chromosomally abnormal abortuses. Triploidy (3n = 69 chromosomes) is approximately three times more common than tetraploidy (4n = 92 chromosomes).
People suffering from infertility, delivery of children with chromosomal abnormalities, recurrent abortions, abnormal findings in prenatal chromosomal analysis, suspicion of Dysmorphic Syndrome, Suspicion of gonosomal abnormalities are advised to analyze their chromosomes..
Understand Biological Age
vs Chronological Age
Purpose of Test
- Telomeres are structures at the ends of chromosomes. It's main function is to act as “caps” to protect genes in process of cellular division. Each time a cell divides a portion of the telomere is eroded slightly (a phenomenon known as the “end-replication problem”). When the telomeres reach a critically short length, cell division stops and these cells enter replicative senescence or apoptosis, and eventually die.
- Critically short telomeres contribute to the onset of chronic and age-related diseases including heart disease, Type 2 Diabetes, some cancers, among other pathologies.
Telomere length serves as the biomarker of the cell's replicative capacity, which defines the biological age of the individual. Hence it is an excellent indicator of an individuals’ overall general health status. Secondly, by knowing the biological age one can get a better understanding of the lifestyle habits that impact the aging process. This affords the opportunity to make appropriate changes. Periodic re-testing to measure the results can help monitor the progress. Thirdly, the test will allow for more personalized medicine as doctors are increasingly treating patients taking into consideration their biological age.
How to Order
- Fill out the enquiry form
- Complete & send the enquiry form
- Laboratory will contact you within 24-48 hours to schedule an appointment for sample collection
Note: If you are not a resident of Dubai, Abu Dhabi, or Sharjah, we will help you find a local laboratory for sample collection
- If required, a link to online payment will be sent along with appointment details
- Else payment can be made in the lab before sample collection
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Everyone has 23 pairs of chromosomes, 22 pairs of autosomes and one pair of sex chromosomes. The science that relates to the study of these chromosomes is referred to as Cytogenetics. Our tests that we offer, analyzes the whole chromosome and identifies any disorders present.
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