deCODE T2TM - Genetic Risk for Type 2 Diabetes
deCODE AFTM- Genetic Risk for Type 2 Atrial Fibrillation
deCODE Breast Cancer TM - Genetic Risk for Breast Cancer
deCODE ProCaTM - Genetic Risk for Prostate Cancer
deCODE GlucomaTM - Genetic Risk for Glucoma
Eastern Biotech offers a novel, noninvasive, DNA-based reference
laboratory test for 4 well-validated genetic risk markers for
type 2 diabetes- including TCF7L2 gene. This helps identify patients
at increased risk of developing type 2 diabetes to help patients
and physicians take early steps to prevent disease before it starts.
Physicinas may work more intensively with higher-risk patients
to encourage lifestyle changes and patients in turn may be more
motivated to comply.

1. Detects SNPs in TCF7L2, CDKAL1, CDKN2A, and PPARG genes that
confer up to a 2.2 fold increased risk for type 2 diabetes comapred
to the general population
2. Overweight prediabetics with a high-risk genetic profile have
50-7-% absolute risk of converting to type 2 diabetes within 3-4
years
3. 36% of patients positive for TCF7L2 marker react to sulfonylurea
treatment compared to 62% who were negative for the test
4. Physicians can identify test-positive patients, who accoount
for about 20% of type 2 diabetes, to determine whether alternative
therapies are more appropriate

1. Order through our online payment section by clicking the button
next to the test.
2. A staff from Eastern Biotech will contact you and provide
all necessary information.
3. A DNA cheek swab sampling kit’ will be sent out to you
my courier whereby you will be asked for a sample of both persons
requiring testing. Our courier will collect the sample from your
home/office.
4. Your sample will be processed at our affiliate laboratory
and the report will be delivered to you by email and also by post.
5. Reporting: The DNA of both individuals is cross matched using
sophisticated DNA analysis techniques, and a report is sent out
to you.

deCODE AFTM is the first and only genetic test that offers insight
into an individual's likelihood of having atrial fibrillation
(AF)- a common but difficult-to-detect cause of ischemic stroke.
Even when the ECG is negative, deCODE AFTM test helps you identify
at-risk AF patients for anticoagulant therapy.

1. 5.7% to 14.3% of hospitalized patients discharged with stroke
of unknown etiology are likely to have intermittent AF missed
by routine cardiac monitoring
2. Current guidelines recommend that ischemic stroke patients
without confirmed AF be discharged on antiplatelet medications
rather than warfarin
3. Antiplatelet agnets have minimal effcet on reducing stroke
rates in AF - about 20% Vs 70% for warfarin

1. Order through our online payment section by clicking the button
next to the test.
2. A staff from Eastern Biotech will contact you and provide
all necessary information.
3. A DNA cheek swab sampling kit’ will be sent out to you
my courier whereby you will be asked for a sample of both persons
requiring testing. Our courier will collect the sample from your
home/office.
4. Your sample will be processed at our affiliate laboratory
and the report will be delivered to you by email and also by post.
5. Reporting: The DNA of both individuals is cross matched using
sophisticated DNA analysis techniques, and a report is sent out
to you.
deCODE Breast Cancer™ is a DNA-based test for multiple risk
factors shown to confer risk for the common form of breast cancer.
The test identifies 7 genetic variants associated with a highre
likelihood of developing breast cancer independent of family history.
This offers physicans the opportunity to begin advanced screening
or initiate early treatment in those who are at increased risk.
1. The test multiplies the individual risk markers to create
a genetic proifile that defines the relative risk of developing
breast cancer, ranging from 0.4-(no risk variants) to approximately
4-fold (all 7 risk variants) compared with the general population
2. Genetic risk defined by the test is independent of convetional
risk factors for breast cancer, including family history, which
are used to determine which higher-risk women benefit from more
intensive management to detect or prevent breast cancer
3. Patients with a higher risk (>20% lifetime risk) may benefit
from more intensive screening with magnetic resonance imaging
(MRI) in addition to routine mammography as recommended
4. Women under 60 years of age with a higher genetic risk may
be candidates for preventive treatment
5. Some of the markers in the test modulate the lifetime risk
for early breast cancer in BRCA1 and BRCA2 mutation carriers

1. Order through our online payment section by clicking the button
next to the test.
2. A staff from Eastern Biotech will contact you and provide
all necessary information.
3. A DNA cheek swab sampling kit’ will be sent out to
you my courier whereby you will be asked for a sample of both
persons requiring testing. Our courier will collect the sample
from your home/office.
4. Your sample will be processed at our affiliate laboratory
and the report will be delivered to you by email and also by
post.
5. Reporting: The DNA of both individuals is cross matched
using sophisticated DNA analysis techniques, and a report is
sent out to you.

Eastern Biotech offers the first genetic test to measure multiple
markers of prostate cancer risk, independent of family history.
The test identifies 8 genetic variants that are associated with
increased risk of prostate cancer. Positive results carry relative
risks ranging from 0.33 to over 6-fold compared to the general
population.
1. About 20% of the general population has a combination of variants
that carry a relative risk of 1.7, 10% carry a 2-fold relative
risk, and 1% carry a >3-fold relative risk. For example, a
2-fold risk in while males trasnlates t a lifetime risk of 32%
(2X16% baseline risk)
2. Risk is independent of family history, which is the only other
risk factor for prostate cancer in white patients. Risk due to
family history may be multiplied by risk from the genetic profile
3. Two of the markers in particular also offer additional insight
into the aggressiveness of the disease

1. Order through our online payment section by clicking the button
next to the test.
2. A staff from Eastern Biotech will contact you and provide
all necessary information.
3. A DNA cheek swab sampling kit’ will be sent out to
you my courier whereby you will be asked for a sample of both
persons requiring testing. Our courier will collect the sample
from your home/office.
4. Your sample will be processed at our affiliate laboratory
and the report will be delivered to you by email and also by
post.
5. Reporting: The DNA of both individuals is cross matched
using sophisticated DNA analysis techniques,
and a report is sent out to you.
deCODE Glaucoma™ is a reference laboratory DNA test for
assessing an inherited risk factor for exfoliation glaucoma, a
major subtype of the group of eye disorders termed Glaucoma. The
test detects versions of markers called SNPs (single nucleotide
polymorphisms) – a one letter variation in the sequence
of the genome, more specifically on chromosome 15 - that deCODE
has linked to an increased risk of exfoliation glaucoma.
Research has shown two sequence variants in a gene called LOXL1
that significantly increase the risk of developing exfoliation
glaucoma. The effect is thought to be through what is called exfoliation
syndrome which is characterized by accumulation of abnormal microfibrillar
deposits that line the aqueous bathed surfaces of the anterior
segment of the eye.

1. According to deCODE’s research the effect of the identified
genetic risk variants seem to be in addition to and independent
of other known risk factors such as intraocular pressure and age.
This means that even though at this point in time there is no
known remedy or actions that can be specifically taken to counteract
the genetic risk associated with the LOXL1 variants, the overall
risk for vision loss as a consequence of undetected exfoliation
glaucoma may be decreased through frequent eye exams and physician
recommended interventions.
2. Independent of the family history for glaucoma knowing ones
genetic make-up in regard to deCODE’s genetic exfoliation
glaucoma risk markers is relevant since they may be part of
the familial risk or an addition to it.
3. The deCODE Glaucoma™ test therefore offers a new factor
and added weight to the analysis of an individual’s risk
for glaucoma which may help the individual and his/her physician
to decide on future monitoring,
prevention and/or specific treatments.

1. Order through our online payment section by clicking the button
next to the test.
2. A staff from Eastern Biotech will contact you and provide
all necessary information.
3. A DNA cheek swab sampling kit’ will be sent out to
you my courier whereby you will be asked for a sample of both
persons requiring testing. Our courier will collect the sample
from your home/office.
4. Your sample will be processed at our affiliate laboratory
and the report will be delivered to you by email and also by
post.
5. Reporting: The DNA of both individuals is cross matched
using sophisticated DNA analysis techniques,
and a report is sent out to you.
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